interaction of phthalocyanine with egg albumin and bovine serum albumin

the interaction of bovine serum albumin ( bsa) and egg albumin with water solublephthalocyanine, cobalt (ιι) 4, 4′ , 4′′, 4′′′- tetrasulfophthalocyanine ( cotspc) , has been studiedby the uv- vis method at ph 7.0 and five different temperatures 20, 25, 30, 35 and 40°c. theformation constants have been elucidated by using spectrophotometric titration and computersquad program data refinement. the thermodynamic parameters δh°, δg°and δs° at 5 differenttemperatures were calculated. the results showed that the best fitting corresponds to a 1: 1complex model between bsa and egg albumin with cotspc. formation constants decrease withincreasing temperature.the formation constants showed that bonding effect between egg albuminand cotspc is stronger than bsa.